Progressive Supranuclear Palsy

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Is a:
  • Disease or Syndrome
Definition:
A degenerative disease of the central nervous system characterized by balance difficulties; ocular motility disorders (supranuclear ophthalmoplegia); dysarthria; swallowing difficulties; and axial dystonia. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal mesencephalon; subthalamic nucleus; red nucleus; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
Synonyms:
  • Ophthalmoplegia, Progressive Supranuclear
  • Ophthalmoplegias, Progressive Supranuclear
  • Palsy, Progressive Supranuclear
  • Progressive Supranuclear Ophthalmoplegia
  • Progressive Supranuclear Ophthalmoplegias
  • Progressive Supranuclear Palsies
  • Progressive Supranuclear Palsy
  • Steele Richardson Olszewski Disease
  • Steele Richardson Olszewski Syndrome
  • Steele-Richardson-Olszewski Disease
  • Steele-Richardson-Olszewski Syndrome
  • Supranuclear Ophthalmoplegia, Progressive
  • Supranuclear Ophthalmoplegias, Progressive
  • Supranuclear Palsies, Progressive
  • Syndrome, Steele-Richardson-Olszewski
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