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Definition: Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial gigantism of the hands and/or feet, asymmetry of the limbs, plantar hyperplasia, hemangiomas (hemangioma), lipomas (lipoma), lymphangiomas (lymphangioma), epidermal nevi, macrocephaly, cranial hyperostosis, and long-bone overgrowth. Joseph Merrick, the so-called "elephant man", apparently suffered from Proteus syndrome and not neurofibromatosis, a disorder with similar characteristics. |
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Synonyms: - Elephant Man Disease
- Proteus Like Syndrome
- Proteus-Like Syndrome
- Syndrome, Proteus-Like
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