Osteoporosis: Babić-Naglić D

Curković B, Grazio S, Babić-Naglić D, Anić B, Vlak T, Hanih M, Anonymous00020. · Hrvatsko reumatolosko drustvo HLZ-a, Subićeva 9, 10000 Zagreb. · Reumatizam. · Pubmed #19024267 No free full text.

Abstract: Osteoporosis is a disease characterized by loss of bone mass and the structural deterioration of bone tissue leading to increased bone fragility and fractures. Preventive measures for osteoporosis and osteoporotic fractures include adequate calcium and vitamine D intake, adequate physical activity and reduction of the risk factors can be influenced. Currently, measurement of bone mineral density using dual energy x-ray absorptiometry (DXA) is still the gold standard for the diagnosis of osteoporosis. Non-pharmacological therapy is the integral part of the management ofosteoporosis. Nitrogen-containing bisphosphonates in weekly or more prolonged (monthly) dosing intervals are now the firstline osteoporosis therapy. Oral bisphosphonates show, generally, similar efficacy on vertebral fractures risk reduction. There, might be some differences among bisphosphonates, regarding risk reduction of non-vertebral, hip and glucocortiocoid related fratures. On behalf of Croatian Society of Rheumatology of Croatian Medical Association we propose recommendations for the prevention, diagnosis and management ofpostmenopausal osteoporosis.

Babić-Naglić D. · Klinika za reumatske bolesti i rehabilitaciju, Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb. · Reumatizam. · Pubmed #17580553 No free full text.

Abstract: Exercise and prevention of falls are the cornerstone of nonpharmacological treatment of osteoporosis (OP). Mechanical stress has osteogenic properties. Proprioceptive training can improve balance. Intermittent mechanical stimuli are most appropriate type of functional bone adaptation. Recommendations for exercises include type (aerobic, weight-bearing, resistance), frequency (minimum 3x weekly), duration (minimum 20-30 minutes) and intensity of 50-80% of repetitive maximum (RM). Target muscle groups for intervention are spine extensors and hip muscles. Eliminaton of risk of falls and proprioceptive exercises can reduce incidency of falls and related fractures.

Babić-Naglić D. · Klinika za reumatske bolesti i rehabilitaciju Medicinskoga fakulteta Sveucilista u Zagrebu Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb. · Reumatizam. · Pubmed #15098378 No free full text.

Abstract: Bone fracture is the most serious outcome of osteoporosis. Main goal of treatment is fracture prevention. Clinical anti-fracture effect is higher than bone mineral density (BMD) increase. The previous fracture is bad prognostic sign. Good therapeutic outcomes are related to early diagnosis and treatment of osteoporosis before fracture is present. Therapeutic decision must be based on longterm risk and benefit ratio and keep in mind skeletal and desirable extraskeletal effects of drugs.