Neurosyphilis

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Is a:
  • Disease or Syndrome
  • Sign or Symptom
Definition:
Infections of the central nervous system caused by treponema pallidum which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as brain infarction. The infection may also remain subclinical for several years. Late syndromes include general paresis; tabes dorsalis; meningeal syphilis; syphilitic optic atrophy; and spinal syphilis. General paresis is characterized by progressive dementia; dysarthria; tremor; myoclonus; seizures; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Synonyms:
  • Asymptomatic Neurosyphilis
  • Central Nervous System Syphilis
  • General Paralyses
  • General Paralysis
  • General Pareses
  • General Paresis
  • General Paresis of the Insane
  • Gummatous Neurosyphilis
  • Juvenile Neurosyphilis
  • Juvenile Pareses
  • Juvenile Paresis
  • Neurosyphilis, Asymptomatic
  • Neurosyphilis, Gummatous
  • Neurosyphilis, Juvenile
  • Neurosyphilis, Paretic
  • Neurosyphilis, Secondary
  • Neurosyphilis, Symptomatic
  • Paralyses, General
  • Paralysis, General
  • Pareses, General
  • Pareses, Juvenile
  • Paresis, General
  • Paresis, Juvenile
  • Paretic Neurosyphilis
  • Secondary Neurosyphilis
  • Syphilis, Central Nervous System
  • Syphilis, CNS
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