Multiple Endocrine Neoplasia Type 2b

  Topic:  
Hints · Remembered Topics    
  Start Here  Overview  World Articles  Find Experts  Books & DVDs  Help 
Helpful information about Multiple Endocrine Neoplasia Type 2b. To learn more about this topic, click the World Articles tab. To find experts on this topic, click the Find Experts tab. To find books and DVDs you can purchase, click the Books & DVDs tab.
Is a:
  • Neoplastic Process
Definition:
Similar to men2a, it is also caused by mutations of the men2 gene, also known as the ret proto-oncogene. Its clinical symptoms include medullary carcinoma (carcinoma, medullary) of thyroid gland and pheochromocytoma of adrenal medulla (50%). Unlike men2a, men2b does not involve parathyroid neoplasms. It can be distinguished from men2a by its neural abnormalities such as mucosal neuromas on eyelids; lip; and tongue, and ganglioneuromatosis of gastrointestinal tract leading to megacolon. It is an autosomal dominant inherited disease.
Synonyms:
  • MEA 2b
  • MEA IIb
  • MEN 2b
  • MEN 3
  • MEN IIb
  • MEN III
  • MEN2b
  • Mucosal Neuroma Syndrome
  • Multiple Endocrine Neoplasms Type 2b
  • Neoplasia, Multiple Endocrine Type 2b
  • Neoplasms, Multiple Endocrine Type 2b
  • Neuroma Syndrome, Mucosal
Broader Topics:
Narrower Topics:
  • None
Possibly Related Topics:
  • List of topics based on word similarity