MPTP Poisoning

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Is a:
  • Disease or Syndrome
  • Injury or Poisoning
Definition:
A condition caused by the neurotoxin mptp which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (parkinson disease, secondary). mptp toxicity is also used as an animal model for the study of parkinson disease. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
Synonyms:
  • MPTP Induced Degeneration of the Striatum
  • MPTP Induced Parkinsonism
  • MPTP Neurotoxicity Syndrome
  • MPTP Neurotoxicity Syndromes
  • MPTP-Induced Degeneration of the Striatum
  • MPTP-Induced Parkinsonism
  • Neurotoxicity Syndrome, MPTP
  • Neurotoxicity Syndromes, MPTP
  • Parkinsonism, MPTP-Induced
  • Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
  • Poisoning, MPTP
Broader Topics:
Narrower Topics:
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