Mixed Connective Tissue Disease

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Is a:
  • Disease or Syndrome
Definition:
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
Synonyms:
  • Connective Tissue Disease, Mixed
  • MCTD
  • Sharp Syndrome
  • Syndrome, Sharp
Broader Topics:
Narrower Topics:
  • None
Possibly Related Topics: