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Review Is there a need for dietary measures to further reduce LDL cholesterol in patients with type II diabetes mellitus on statin therapy? 2008
Winters SM, Visser H, Steerneman AH, Thomas G, Bots ML, van der Heijden GJ. · Julius Center for Health Sciences and Primary Care, Str. 6.131, Heidelberglaan 100, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands. · Prim Care Diabetes. · Pubmed #18684421 No free full text.
Abstract: PURPOSE: To study the need for dietary measures to further reduce LDL cholesterol in patients with type 2 diabetes mellitus on statin therapy. METHODS: A Pubmed, Embase, CINAHL and Cochrane library search was performed to identify relevant articles. After critical appraisal six articles were ranked according to relevance, validation and level of evidence. RESULTS: There were no studies performed among type II diabetics. Among patients with hypercholesterolaemia, diet led to an additional LDL reduction from 0.20 to 0.88 mmol/l, translating into 23% reduction in vascular risk. CONCLUSION: We recommend a low-fat diet on top of statin therapy in patients with type 2 diabetes mellitus assuming that effects found in hypercholesterolaemic patients also apply to type 2 diabetics.
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