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Review Metabolic derangements in an adult patient with tetralogy of Fallot: possible role of chronic systemic hypoxia. 2007
Harada E, Yasue H, Mizuno Y, Ito T, Sakaino N, Yasue S, Masuzaki H. · Division of Cardiovascular Medicine, Kumamoto Kinoh Hospital, Kumamoto Aging Research Institute, 6-8-1 Yanamuro, Kumamoto City, Japan. · Am J Med Sci. · Pubmed #18030188 No free full text.
Abstract: The metabolic disorders associated with chronic hypoxemia in adult patients with tetralogy of Fallot (TOF) have not been fully appreciated. We report a 53-year-old male patient with TOF who presented with fasting hypoglycemia, hypertriglyceridemia, increased blood levels of free fatty acids, adiponectin, B-type natriuretic peptide, and uric acid. The cluster of these metabolic derangements has not been previously reported, and the possible role of chronic hypoxia in the production of these disturbances is discussed with a review of pertinent literatures.
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