Hyperlipidemias: Dominiczak MH

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A digest of articles written 1999 and later, on the topic "Hyperlipidemias," originating from Planet Earth —» Dominiczak MH.  Display:  All Citations ·  All Abstracts
1 Editorial Hyperlipidaemia and cardiovascular disease: apolipoprotein measurements and metabolic syndrome as predictors of cardiovascular risk. 2008

Deans KA, Dominiczak MH. · Department of Biochemistry, Gartnavel General Hospital, Glasgow, UK. · Curr Opin Lipidol. · Pubmed #18957887 No free full text.

This publication has no abstract.

2 Editorial Hyperlipidaemia and cardiovascular disease: nonfasting triglycerides gain momentum--but nothing changes on the metabolic syndrome front. 2008

Dominiczak MH. · No affiliation provided · Curr Opin Lipidol. · Pubmed #18460927 No free full text.

This publication has no abstract.

3 Editorial Hyperlipidaemia and cardiovascular disease: triglycerides--new evidence for links with atherogenesis? 2005

Dominiczak MH. · No affiliation provided · Curr Opin Lipidol. · Pubmed #16276249 No free full text.

This publication has no abstract.

4 Editorial Hyperlipidaemia and cardiovascular disease. 2002

Dominiczak MH. · No affiliation provided · Curr Opin Lipidol. · Pubmed #12045405 No free full text.

This publication has no abstract.

5 Editorial Hyperlipidaemia and cardiovascular disease. 2001

Dominiczak MH. · No affiliation provided · Curr Opin Lipidol. · Pubmed #11353340 No free full text.

This publication has no abstract.

6 Editorial Hyperlipidaemia and cardiovascular disease. 2000

Dominiczak MH. · No affiliation provided · Curr Opin Lipidol. · Pubmed #10750700 No free full text.

This publication has no abstract.

7 Article Efficacy of statin therapy: possible effect of phenytoin. free! 1999

Murphy MJ, Dominiczak MH. · Department of Biochemistry, Gartnayel General Hospital, Glasgow, UK. · Postgrad Med J. · Pubmed #10435174 links to  free full text

Abstract: Statins are currently the most widely prescribed lipid-lowering drugs. Individual statins are known to be metabolised by the CYP3A4 isoform of the cytochrome P450 system. The effect of CYP3A4 inducers such as phenytoin on the metabolism and efficacy of these agents is unknown. We report a patient with familial hypercholesterolaemia and epilepsy in whom the introduction and subsequent discontinuation of phenytoin were associated with marked changes in the lipid response to treatment with simvastatin and atorvastatin. The serum activity of gamma-glutamyl transpeptidase may have acted as a marker of microsomal induction by phenytoin, since it rose markedly when phenytoin was introduced and returned to normal after it was discontinued.