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Review HIV-GB virus C co-infection: an overview. 2009
Baggio-Zappia GL, Hernandes Granato CF. · Infectious Disease Discipline, Laboratory of Virology, Federal University of São Paulo, São Paulo, Brazil. · Clin Chem Lab Med. · Pubmed #19055469 No free full text.
Abstract: GB virus C (GBV-C) and hepatitis G virus (HGV) are two isolates of the same virus, independently identified in humans in the 1990s by two research laboratories, and were initially considered a potential cause of liver disease. Studies failed to associate the virus with hepatitis or any known human disease. GBV-C reappeared in the scientific scene when some research groups, in an attempt to find the interference of the virus among HIV seropositive patients, reported a lower mortality rate and slower disease progression among co-infected patients. From then on, several mechanisms have been proposed to clarify this putative benefit; however, the question whether GBV-C exerts a protective effect in HIV-infected patients remains to be resolved.
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