Chronic Fatigue Syndrome: Lavoie S

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A digest of articles written 1999 and later, on the topic "Fatigue Syndrome, Chronic," originating from Planet Earth —» Lavoie S.  Display:  All Citations ·  All Abstracts
1 Article Gabapentin-induced myopathy in 2 patients on short daily hemodialysis. 2005

Lipson J, Lavoie S, Zimmerman D. · Ottawa Hospital, Department of Medicine, Kidney Research Centre, University of Ottawa, Ontario, Canada. · Am J Kidney Dis. · Pubmed #15957120 No free full text.

Abstract: Gabapentin is an antiepileptic medication that also has been used for restless legs syndrome. The mechanism of action is unknown. The most commonly reported adverse effects of this medication include somnolence, dizziness, ataxia, fatigue, nystagmus, and tremor. Myalgia has been reported in 2% of gabapentin users compared with 1.9% of patients in placebo-controlled add-on trials. Two patients on short daily hemodialysis therapy developed neuromuscular symptoms and an elevation in creatine kinase levels after starting gabapentin therapy. To our knowledge, this is the first case report of an increase in creatine kinase level after the administration of gabapentin.