Chediak-Higashi Syndrome

Overview

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Is a:

Disease or Syndrome

Definition:

A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.

Synonyms:

Chediak Higashi Syndrome
Syndrome, Chediak-Higashi

Broader Topics:

Phagocyte Bactericidal Dysfunction

Narrower Topics:

Aleutian Mink Disease

Possibly Related Topics:

List of topics based on word similarity