Caplan Syndrome: Reynolds CA

  Topic:  
Hints · Remembered Topics    
  Start Here  Overview  World Articles  Find Experts  Books & DVDs  Help 
 
Column View Map One Article   Help
A digest of articles written 1999 and later, on the topic "Caplan Syndrome," originating from Planet Earth —» Reynolds CA.  Display:  All Citations ·  All Abstracts
1 Article Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania. 2007

Carlson T, Reynolds CA, Caplan R. · UCLA Semmel Institute of Neuroscience and Human Behavior, UCLA Medical Center, Los Angeles, CA 90024, USA. · J Am Acad Child Adolesc Psychiatry. · Pubmed #17314721 No free full text.

Abstract: This case report describes two children who developed hyperammonemia together with frank manic behavior during treatment with a combination of valproic acid and risperidone. One child had been maintained on valproic acid for years and risperidone was added. In the second case, valproic acid was introduced to a child who had been treated with risperidone for years. In both cases, discontinuing the valproic acid resulted in normalization of ammonia levels and cessation of the manic behavior. This case report alerts physicians to the importance of obtaining serum ammonia levels in children treated with valproic acid and risperidone who present with manic behavior.