Replacement Arthroplasty: Neyret P

Lustig S, Bruderer J, Servien E, Neyret P. · No affiliation provided · Knee. · Pubmed #19138856 No free full text.

This publication has no abstract.

Lustig S, Servien E, Biedert R, Neyret P. · Centre Albert Trillat, Hôpital de la Croix-Rousse, Grande Rue de la Croix-Rousse 103, F-69317 Lyon, France. · Orthopade. · Pubmed #18719888 No free full text.

Abstract: In the majority of cases, arthrosis of the patellofemoral joint (PFJ) is combined with arthrosis of the femorotibial compartment and thus assumes a somewhat secondary role. Nevertheless, it can occur as an isolated entity. Several radiological studies evidenced isolated degenerative alterations in the PFJ in the age group >55 years (13.6-24.0% in women and 11.0-15.4% in men). In younger patients the incidence is lower and is mainly associated with patellar instability or post-traumatic arthrosis. Just the same, the choice of appropriate treatment for these patients is challenging. Total replacement can be recommended for older and less active patients. In contrast, for younger and more active patients, various conservative treatment options and more demanding operative techniques are available to the surgeon to avoid arthroplasty. This article describes the different therapeutic possibilities for managing arthrosis of the PFJ in patients aged <50 years.

Yercan HS, Ait Si Selmi T, Sugun TS, Neyret P. · Department of Orthopaedics and Traumatology, Medical Scholl of Celal Bayar University, Manisa, Turkey. · Knee. · Pubmed #16137888 No free full text.

This publication has no abstract.

Yercan HS, Ait Si Selmi T, Sugun TS, Neyret P. · Department of Orthopaedics and Traumatology, Medical Scholl of Celal Bayar University, Manisa, Turkey. · Knee. · Pubmed #15993602 No free full text.

Abstract: Tibiofemoral instability following total knee replacement has received little attention. However it is a cause of early and late failure and usually requires revision surgery. Several factors may be implicated including improper soft tissue balancing, flexion-extension gap mismatch and acute ligamentous injuries. Meticulous surgical technique and proper prosthetic selection at the primary procedure avoids this complication.

Pinaroli A, Piedade SR, Servien E, Neyret P. · Knee Surgery Department, Livet Hospital, Albert-Trillat Center, 8, rue de Margnolles, 69300 Caluire, France. · Orthop Traumatol Surg Res. · Pubmed #19423419 No free full text.

Abstract: INTRODUCTION: Intraoperative fractures are a reported complication during the course of primary total knee replacement. Major ligament disruptions can also occur. Clinical data are lacking to tell how much these incidents affect implantation quality and outcome. HYPOTHESIS: A thorough knowledge of these occasional incidents helps proper decision making when confronted to such situations at surgery. MATERIALS AND METHODS: This report is based on a series of primary, posterostabilized total knee arthroplasties (posterostabilized, mobile bearing TKA with a third median condyle from Tornier Laboratory). We studied all possible mechanical complications that developed during the course of arthroplasty and analyzed their cause. We compared the functional results of patients presenting these complications to those of the total series and to data from the literature. The entire operative reports for the 1795 TKA performed during this study were available and evaluated. A clinical and radiological review was performed for 1624 patients at an average follow-up time of 36.8+/-34 (2-193) months. RESULTS: At this last follow-up, the average International Knee Society (IKS) score was 91.2 (19-100) and the function score was 77.76 (0-100). One hundred and thirty-two patients were deceased (unrelated to TKA) at this last follow-up evaluation. A total of 69 mechanical complications were accounted for at the time of surgery (3.8%): 40 definite fractures or fissures around the knee (2.2%), 29 tendon or ligament disruptions or attenuations (1.6%). The risk of tibial cracks was statistically more significant, with the smaller sizes tibial trays (size 1) (p=0.019) or when an anterior tibial tuberosity elevation had been performed (p=0.02). Survival curve analysis (at an average seven and a half-years postoperative follow-up) showed that all prosthetic components were still present in 93.3% of cases in the series of patients with these peroperative complications, and in 93.8% of cases in the series of patients without these intraoperative complications; this survival rate amounted to 91.9% of cases at an average 16-years postoperative follow-up. CONCLUSION: This large, homogeneous series of primary, posterostabilized TKA took on 3.8% of intraoperative bone or ligament complications. All these complications could be prevented by a rigorous surgical technique. The improvement of ancillary materials, the saws, and good knowledge of such complications by the surgeon are essential. LEVEL OF EVIDENCE: Level IV. Therapeutic Study.

Lustig S, Paillot JL, Servien E, Henry J, Ait Si Selmi T, Neyret P. · Knee Surgery Department, centre Livet, Albert Trillat Center, North Hospitals Group, 8, rue de Margnolles, 69300 Caluire, France. · Orthop Traumatol Surg Res. · Pubmed #19251232 No free full text.

Abstract: Unicompartimental knee arthroplasty outcome is sometimes compared to total knee arthroplasty but various implant parameters might greatly influence this outcome. The objectives of this study were to report the results of a consecutive series of 172 all-polyethylene unicompartmental knee arthroplasties (UKAs) and to detail possible factors of success and failure. HYPOTHESIS: It is possible to outline implant and technique factors determining success or failure in unicompartimental knee arthroplasty. MATERIALS AND METHODS: One hundred seventy-two HLS-type cemented resurfacing UKAs, with the femoral implant made of chrome-cobalt and the tibial implant tibial entirely in polyethylene (without anchorage studs) were consecutively implanted between 1988 and 2004 in 134 patients (111 females and 23 males) in our center according to the indications established in 1988, using the same technique for each surgery. The patients' mean age was 72.2 years (range, 25-90 years). The review rate was 83.7% (144 UKAs), with a mean follow-up of 62.3 months (range, 24-160 months). The series included 84 medial UKAs and 60 lateral UKAs. The clinical data were analyzed using the IKS criteria and the patients had a complete radiological evaluation before surgery and at the last follow-up. RESULTS: The rate of satisfied or very satisfied patients was 97.2%. No pain or slight pain was found in 81% of the cases. The mean flexion was 133 degrees (range, 85-150 degrees). The mean knee score varied from 63.6 before surgery to 91.5 (90.4 for medial UKAs and 92.9 for lateral UKAs) and the function score from 63.6 to 83.8 (84.7 for medial UKAs and 82.6 for lateral UKAs). The mean range of motion was 133 degrees (range, 85-150 degrees), better than the medial UKAs for osteonecrosis. The mean residual deformity was 4 degrees varus for the medial UKAs and 2 degrees valgus for the lateral UKAs. A radiolucency was found in 23% of the cases (20% tibial and 3% femoral), nonprogressive in all cases. In 87.2% of the cases, the opposite femorotibial compartment remained radiologically normal. No progression to osteoarthritis in the femoropatellar joint required additional surgery. Sixteen patients required revision surgery: in six cases, the implant was removed and a total prosthesis implanted (one late infection, one case of involvement of the opposite compartment, and four cases of tibial component loosening). In the other cases, one tibial baseplate was changed, five arthroscopies were done, and four unicompartmental knee replacements were done on the opposite compartment. The Kaplan-Meier survival rate (taking into account the revisions with implant change) was 95.6. The results of this series were very satisfactory and were similar to recent series in the world literature that showed survival rates between 90 and 98% at 10 years, rates that are equivalent to those found for total knee replacements. The mean flexion range of motion found was higher than the majority of other recent series, probably because of the precise patient selection in the present study, a minimally invasive approach, and the femoral implant design with an ascending condylar posterior cut. The deterioration of the contralateral compartment is frequently reported, but was perhaps prevented by the absence of overcorrection and patient selection. In this series, none of the UKAs was revised for wear. We explain this by the systematic preservation of a moderate undercorrection, particularly for medial UKAs, the quality of the polyethylene, and a selection based on patient weight and age. CONCLUSIONS: The option of an all-polyethylene tibial implant, with minimal bone cuts (femoral resurfacing), makes excellent long-term results possible.

Piedade SR, Pinaroli A, Servien E, Neyret P. · Department of Orthopedics and Traumatology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, Brazil. · Knee Surg Sports Traumatol Arthrosc. · Pubmed #19099293 No free full text.

Abstract: According to literature, knee arthroscopy is a minimal invasive surgery performed for minor surgical trauma, reduced morbidity and shortens the hospitalization period. Therefore, this type of surgery before total knee arthroplasty (TKA) could be considered a minor procedure with minimum postoperative complication. A retrospective and cohort series of 1,474 primary TKA was performed with re-assessment after a minimum follow-up period of 2 years: 1,119 primary TKA had no previous surgery (group A) and 60 primary TKA had arthroscopic debridement (group B). All the patients underwent a clinical and radiological evaluation as well as IKS scores. Statistical analysis of postoperative complications revealed that group B had a higher postoperative complication rate (P < 0.01). In this group, 30% of local complications were re-operated and 8.3% of these cases underwent revision TKA (P < 0.01). The mean interval between arthroscopy and primary TKA was 53 months. However, statistical analysis did not reveal a direct correlation between arthroscopy/primary TKA interval and postoperative complications/failures (P = 0.55). The Kaplan-Meier survival curves showed a survival rate of 98.1 and 86.8% at 10 years follow-up for groups A and B, respectively. Our data allow us to conclude that previous knee arthroscopy should be considered a factor related to postoperative primary TKA outcomes as demonstrated by the higher rate of postoperative complications and failures (P < 0.001) as well as a worse survival curve than group A.

Piedade SR, Pinaroli A, Servien E, Neyret P. · Department of Orthopedics and Traumatology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, Brazil. · Knee Surg Sports Traumatol Arthrosc. · Pubmed #19082578 No free full text.

Abstract: The purpose of this study was to evaluate cases of early aseptic failures presented during the first 5-year follow-up in a group of 981 primary total knee arthroplasty (primary TKA). Predisposing factors as well causes of failures and postoperative complications in different groups of aseptic failures were re-assessed and compared to a control group. A retrospective and cohort study compared one group of 944 primary TKA without surgical revision (890 patients) (Group A) with 22 primary TKA (22 patients) (Group B) that had revision TKA secondary to aseptic failure during the first five years follow-up. The cases of isolated patellar button replacement (n = 8) and infection (n = 7) were not considered in this study. All patients underwent a systematic assessment that included clinical and radiographic examinations, and IKS scores. Aseptic failure was more prevalent at the first 2-year follow-up (63%). TKA loosening (n = 11) and undiagnosed pain (n = 7) were considered the most frequent modes of failures, and laxity (n = 1) was a very rare early cause of failure. The aseptic failure group was characterized as average 5 years younger with a greater number of previous knee surgeries, lower IKS scores improvement, and more postoperative pain compared to control group, despite the fact that the aseptic failure group showed a prevalence of cases during the first 2-year follow-up. Inside this group, the undiagnosed pain group had lower improvement of IKS scores, a remarkable prevalence in prior surgical procedure (71%) and a minor mean interval between primary and revision TKA (11.6 months).

Hannaoui S, Lustig S, Servien E, Aït Si Selmi T, Neyret P. · Al-Hayat hospital, Shayah, Liban. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #18984125 No free full text.

Abstract: PURPOSE OF THE STUDY: Knee pain can be a problem after unicompartmental arthroplasty, compromising the long-term outcome. Arthroscopy may be useful to treat some of the causes such as cement extrusion, fibrous interposition between prosthetic elements, meniscal regeneration, hypertrophic synovitis, or arthroscopic degeneration. We evaluated the results of these procedures. MATERIAL AND METHODS: Seven patients, mean age of 75 years (range 70-79), underwent knee arthroscopy. These patients were among a series of 214 unicompartmental knee prostheses implanted from 1988 to 2005. Arthroscopy was undertaken because of persistent pain after prosthesis implantation. Repeated physical examinations, X-rays and laboratory work-ups were negative for infection or mechanical anomaly. Medical treatment was attempted. The delay before recourse to arthroscopy was 16.3 months (range 9-36 months). The series was composed of five women and two men. RESULTS: Arthroscopy after unicompartmental prosthesis enabled the discovery of chondral, meniscal, and synovial lesions which had not been diagnosed with the usual imaging and laboratory tests. Meniscal regeneration, neomeniscus, and fibrous interpositions were observed. Biopsies were obtained. The arthroscopic procedures performed were: regularization of degenerative contralateral menisci, resection of neomenisci, and synovectomy. Arthroscopic treatment by washout shaving of the cartilage lesions and regularization of the meniscal lesions provided good results. Outcome was scored excellent or good in five knees, and insufficient in two due to progressive degeneration. For one of these two knees, the non-prosthesis femorotibial compartment progressed to overt degeneration. The IKS knee score improved 13 points in the seven patients and the function score 20 points at one to five years follow-up. DISCUSSION: Arthroscopy after unicompartmental prosthesis for knee pain can give good results for unexplained pain, both in terms of diagnosis and in terms of etiological treatment. In certain knees, diagnostic arthroscopy can enable identification of the cause of pain after unicompartmental prosthesis. Therapeutic arthroscopy avoids repeated arthrotomy and shortens recovery time.

Servien E, Saffarini M, Lustig S, Chomel S, Neyret P. · Department of Orthopaedic Surgery, Centre Albert-Trillat, Hopital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France. · Knee Surg Sports Traumatol Arthrosc. · Pubmed #18779949 No free full text.

Abstract: The purpose of this study was to analyze the in vivo dimensions of each tibial plateau for planning of unicompartmental knee arthroplasty (UKA), and to compare the morphometric data to the dimensions of nine current designs of UKA tibial components. Thirty-seven knees (31 females and 6 males) operated on with UKA were studied. All patients were examined postoperatively using computed tomography (CT). There were 18 lateral and 19 medial UKAs. On the CT scan, each operated tibial plateau was measured in the transverse plane at the resection level, just below the full polyethylene tibial component. We measured the length of the anteroposterior (AP) cut as well as the maximal mediolateral dimension of the resected plateau (perpendicular to the AP cut). We compared the measurements with nine current UKA systems: Accuris (Smith and Nephew), Advance (Wright Medical), HLS Uni Evolution (Tornier), Miller-Galante and "ZUK" (Zimmer), Oxford and Oxford alpha (Biomet), Preservation (DePuy) and Unix (Stryker). There was good correlation between patient height and mediolateral dimension (r=0.6), and between patient height and area of total tibial plateau (r=0.7). The anteroposterior dimension was greater for the medial plateau (mean 50.8 mm, SD 3.3) than for the lateral plateau (mean 47.2 mm, SD 3.3). This difference was statistically significant (P=0.0016). Some UKA implants are designed with an asymmetric femoral component, but none have an asymmetric tibial component. The present study suggests, however, that the shape of the medial tibial plateau differs from that of the lateral plateau. This difference can lead to mediolateral overhang for medial UKA, if the surgeon aims for optimal anteroposterior coverage.

Piedade SR, Pinaroli A, Servien E, Neyret P. · Department of Orthopedics and Traumatology, School of Medical Sciences, State University of Campinas, UNICAMP. · Knee. · Pubmed #18771928 No free full text.

Abstract: The objective of this study was to investigate the influence of tibial tubercle osteotomy on postoperative outcome, intra- and postoperative complications, as well as postoperative clinical results and failures in primary total knee arthroplasty (TKA). In a continuous, consecutive series of 1474 primary TKA, we analysed 126 cases where a tibial tubercle osteotomy approach was performed and 1348 cases without tibial tubercle osteotomy. Before surgery, all patients underwent a systematic assessment that included a clinical examination, radiographs (stress hip-knee-ankle film [pangonogram], weight bearing, anteroposterior knee view, schuss view, profile and patellar axial view at 30 degrees, stress valgus and varus view) and International Knee Society scores. When analysing intraoperative complications, tibial plateau fissures or fractures and tibial tubercle fracture were considered as complications relating to the tibial tubercle osteotomy group (p<0.001, p=0.007). With a 2-year minimum follow-up, there was no statistical difference in the number of revisions carried out in the two study groups (p=0.084). However, postoperative tibial tubercle fracture and skin necrosis were significantly related to the osteotomy (p=0.001 and p</=0.001, respectively). Tibial tubercle osteotomy cannot be considered an entirely safe procedure in primary TKA as it is associated with local complications, particularly skin necrosis and fracture of the tibial tubercle. Therefore, tibial tubercle osteotomy should be performed only when necessary, i.e. in cases where there are difficulties gaining adequate surgical exposure, ligament balance and correct implant positioning. The procedure also demands considerable surgical experience to achieve a good outcome.

Debarge R, Lustig S, Neyret P, Ait Si Selmi T. · Service de Chirurgie Orthopédique et Traumatologique, Centre Livet, Hôpital de la Croix-Rousse, Caluire, France. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #18555863 No free full text.

Abstract: PURPOSE OF THE STUDY: For hip prosthesis surgery, the challenge is to obtain optimal function of the instrumented hip but also to eliminate any limb length discrepancy, correct the femur offset and guarantee the center of rotation of the hip joint. Preoperative planning for total hip arthroplasty (THA) enables determination of the appropriate length for the prosthetic neck and the size and eventually the type of implants to use. From a prospective series of 86 patients who underwent first-intention THA for implantation of a noncemented prosthesis, we studied the precision of the outcome as function of the preoperative planning. We also ascertained whether the preoperative planning was sufficient to provide the measurements necessary for correct implant position. MATERIAL AND METHODS: We analyzed a prospective series of patients who underwent first-intention THA from January 2004 through January 2006. To be eligible for inclusion, patients could not have a THA of the contralateral hip. The series was composed of 58 females and 28 males, mean age 70.2 years (range 45-93). The reasons for THA were primary degenerative disease (n=76) and aseptic osteonecrosis (n=10). The contalateral hip was intact and free of osteoarthritis with an anatomic presentation considered to be normal. The standard X-ray protocol included an anteroposterior view of the pelvis in the upright position and 10 degrees internal rotation obtained preoperatively and three months postoperatively. All radiographic measurements were made by the same investigator using a manual nondigitalized technique. We compared planning parameters (pivot size and type, length of the neck, and size of the cup) with the final outcome in order to determine the compliance with the preoperative planning. All operations were performed in the lateral supine position under general anesthesia and by the same surgeon. The posterolateral Moore approach was used. All implants were press fit without cement, both for the cup and for the femoral piece. RESULTS: All planning parameters selected for study (offset, size of the head and the cup, length of the neck) were available for 32 hips, giving an overall conformity of 37%. The length of the neck was as planned in 75% of hips, the size of the cup in 62% and the size of the femoral stem in 64%. The offset defined preoperatively was never changed during the operation. Ideal implantation (+/- 5mm for all criteria selected for study) was obtained in 60% of hips; the height of the center of rotation was reproduced in 81% and the lateralization in 84%. Femur lateralization was reproduced in 75% of the hips and hip offset in 66%. Leg length discrepancy was avoided in 85% of the patients. DISCUSSION AND CONCLUSION: Preoperative planning reliably predicts the final offset of the implanted femoral stem. It is more difficult to predict the size of a press fit cup but in our experience the difference does not greatly affect restitution of the hip anatomy. We readily changed the length of the neck during the operation if necessary and have found that the leg length has been better with this approach. This leads to the observation that all of the planning parameters are not fully accurate because of the magnification effect, anatomic conditions, or possible defective execution. While the overall rate of conformity was low, looking at the results for each element separately provided a useful element for each phase of the operation. We recommend planning a medium length neck so it can be easily changed during the operation. The availability of offset measurements is particularly important to control hip lateralization and leg length. Current advances in computer-assisted surgery should be helpful in improving the imperfections of preoperative planning.

Pinaroli A, Lavoie F, Cartillier JC, Neyret P, Selmi TA. · Orthopedic Surgery Department, Centre Livet, Hôpital de la Croix-Rousse, Caluire, France. · J Arthroplasty. · Pubmed #18534426 No free full text.

Abstract: A conservative approach to femoral revision is assessed. We report on 41 femoral revisions using an extensively coated hydroxyapatite primary femoral stem. Clinical, operative, and radiological data were gathered. Harris hip scores increased from 65/100 to 90/100 at the minimal follow-up of 1 year (P < .05). All stems showed signs of osseous integration. No significant migration was measured. No patient had to be reoperated because of problems related to the stem. Good results are reported for femoral revision with Paprosky type I and II bone defects with no significant difference between the 2 subgroups, hereby proving that conservative femoral revision is a reasonable treatment alternative. Reproducible results with such a technique may bring surgeons to be more aggressive when noticing early signs of femoral loosening.

Leal J, Davies AP, Selmi TA, Neyret P. · Institut Universitari Dexeus, ICATME, Barcelona, Spain. · J Arthroplasty. · Pubmed #18514887 No free full text.

Abstract: Klippel-Trenaunay syndrome (KTS) is a triad of cutaneous hemangiomas, varicose veins, and localized hypertrophy of soft tissue and bone. Orthopedic surgical intervention may be required for the management of localized limb-length discrepancy or joint arthropathy, especially in the lower limb. We describe the management of a 33-year-old patient with a diagnosis of KTS and severe knee arthropathy. After treatment with a posterostabilized, cemented total knee arthroplasty, his range of motion was improved and at 5 years follow-up the clinical outcome was good. We are not aware of any previous reports on the prosthetic management of knee arthropathy in KTS. Precise preoperative diagnosis and analysis of the vascular abnormalities must be undertaken and the case discussed with vascular surgical colleagues as part of the preoperative planning process.

Lustig S, Lavoie F, Selmi TA, Servien E, Neyret P. · Service de Chirurgie Orthopédique, Centre Livet, Hôpital de la Croix-Rousse, 8, rue de Margnolles, 69300 Caluire, Lyon, France. · Knee Surg Sports Traumatol Arthrosc. · Pubmed #18478201 No free full text.

Abstract: Many authors presented the epicondylar axis as the fixed axis of rotation of the femoral condyles during flexion of the knee. Positioning of the femoral component of a total knee arthroplasty (TKA) based on the epicondyles has been proposed. This work is a critical analysis of this concept. Metallic bodies were inserted at the level of collateral ligament insertions on 16 dried femurs, allowing us to locate the surgical epicondylar axis. The dried femurs were studied using standard radiographs and CT-scan. CT cuts were made perpendicular to the epicondylar axis. The medial mechanical femoral angle and the epicondylar angle were measured on the radiographs. The posterior and distal epiphyseal rotations relative to the epicondylar axis (Posterior Condylar Angle, PCA, and Distal Condylar Angle, DCA, respectively) were measured on the CT-scans. PCA and DCA values were compared. The centre of the posterior femoral condyles was located on sagittal reconstructions using the tangent method and was confirmed with circular templates, and then compared to the location of the epicondyles. Circle-fitting of the entire femoral condylar contours centred on the epicondyles was also tried. The mechanical femoral axis was nearly perpendicular to the epicondylar axis but with important variations. The average PCA and DCA were 1.9 degrees +/- 1.8 degrees and 3.1 degrees +/- 2.1 degrees , respectively. No relationship could be established between the mechanical femoral angle and the PCA. The individual differences between the PCA and the DCA averaged 2.2 degrees . A significant distance was found between the centre of the condylar contours and the epicondyles: 6.5 mm in average on the lateral side (range 2.3-11.3 mm) and 8.4 mm on the medial side (range 4.0-11.6 mm). Circle-fitting of the entire medial or lateral femoral condylar contours centred on the epicondyles was not possible. The centre of the posterior femoral condyles is significantly different from the epicondylar axis, thus refuting the conclusions of previous authors. Furthermore, considering the differences between the distal and posterior condylar angles shown here, as well as the difficulty of repeatably locating the epicondyles during surgery, using the epicondylar axis as the only landmark to position the femoral component during a first intention TKA is not recommended. The surgical epicondylar axis does not appear to be an adequate basis for the understanding of the shape of the distal femur.

Debarge R, Nicolle MC, Pinaroli A, Ait Si Selmi T, Neyret P. · Service de Chirurgie Orthopédique et Traumatologique, Centre Albert Trillat, 8, rue Margnolles, 69300 Caluire. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #18065867 No free full text.

Abstract: PURPOSE OF THE STUDY: We report the results of a retrospective analysis of 923 cases of first-intention total knee arthroplasties. The objective was to determine retrospectively the rate of surgical site infections, including all infections diagnosed during the first year, and to search for risk factors. We also wanted to present our surveillance system planned for a 10-year period. MATERIAL AND METHODS: From January 1994 to January 2004, first-intention total knee arthroplasty (TKA) was performed on 999 knees. HLS prostheses were implanted. At minimum 12 months, follow-up data was complete for 923 implants which constituted the study group. Female gender predominated (72%). Mean patient was 71 years (range 26-93). Anterior surgery was performed for 25% of the knees. Etiologies were osteoarthritis (87.5%), and rheumatoid polyarthritis (6.9%). Cefazolin was used for systematic preoperative (one injection) and postoperative (48 hr) antibiotic proxphylaxis. Vancomycin was used for patients with a contraindication for cefazolin. Information was collected from two sources: computerized consultation charts for all follow-up visits completed prospectively since 1995 et data collected by the Hygiene and Epidemiology Unit during the year following implantation. Data on surgical site infections was collected from the hospitalization files, outpatient files and control visits. Each case of infection was validated at an annual interdisciplinary meeting. We retained for analysis deep infections requiring revision surgery with identification of the causal agent on the intraoperative samples. We identified a subgroup of infections occurring during the first postoperative year, the delay generally retained for surgical site infections. RESULTS: Twenty surgical site infections after TKA were identified during the 10-year surveillance period (2.1%). Mean follow-up was 43 months (range 12-123 months, median 37 months). The rate of surgical site infections occurring during the first postoperative year was 1.4%. Eighty-percent of the infections (n=16) occurred within the first two postoperative months. Two infections were diagnosed two to five years after surgery and two others more than five years after surgery due to hematogenous contamination. All of the observed infections involved a single causal germ. Agents identified were: Gram+ (90%) and Gram- (10%), with a clear predominance for Staphylococcus aureus (n=9). Infections developed 2.1-fold more often in patients with an inflammatory disease (rheumatoid polyarthritis). Age and body mass index did not differ between patients with and without surgical site infection. CONCLUSION: The analysis of our series demonstrated the difficulties in conducting long-term surveillance.

Dojcinovic S, Ait Si Selmi T, Servien E, Verdonk PC, Neyret P. · Centre Livet, Hôpital de la Croix Rousse, Hospices Civils de Lyon, 8 rue de Margnolles, 69300 Caluire. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #17646818 No free full text.

Abstract: PURPOSE OF THE STUDY: The purpose of our study was to compare the clinical, functional and radiological results of two types of tibial components for the same total knee prosthesis (posterior stabilized HLS), all-polyethylene (group A) and metal-backed (group B), in order to answer the following question: does use of an all-polyethylene piece affect mid-term outcome of total knee arthroplasty (TKA)? MATERIAL AND METHODS: This was a retrospective comparative analysis of a single-center non-randomized consecutive series of 169 patients with an all-polyethylene posterior stabilized cemented gliding TKA. This series was matched with another retrospective series of 169 posterior stabilized cemented TKA with a metal-backed tibial piece. Matching factors were age, gender, etiology, and follow-up. The two series were extracted from our database which included all patients who underwent surgery for a TKA in the same institution (Lyon Civil Hospices) performed by one of the authors (PN) or under his responsibility between 1987 and 1996 for group A (all-poly) and between 1987 and 1997 for group B (metal-backed). Mean follow-up was 66 months. The IKS scores and radiological findings were recorded. RESULTS: In group A, 96% of patients were satisfied, 93% in group B. The IKS knee score for group A was 89 +/- 10.8 and 88.3 +/- 11.9 for group B. The function score was 68 +/- 23.7 in group A and 71 +/- 24 in group B. Mean flexion was 113 degrees for both groups. Non-progressive lucent lines were noted in 27 cases in group A and 23 in group B. Revision TKA was performed for 18 knees in group A, including six with implant replacement (three of them for infection). In group B, there were ten revisions, seven with implant replacement including one with infection and three without implant replacement. The 10-year survival was 94.5% in group A and 93.64% in group B. There was no significant difference in the function and knee scores, the presence of lucent lines, and the number of implant replacements between group A and group B (p>0.05). DISCUSSION: This study was unable to demonstrate any superiority in clinical and radiological results for TKA between the all-polyethylene and metal-backed options at five years follow-up.

Aït Si Selmi T, Lustig S, Dojcinovic S, Neyret P. · Service de Chirurgie Orthopédique, Centre Livet, Hôpital de la Croix-Rousse, 8, rue des Margnolles, 69300 Caluire-Lyon. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #17245234 links to  free full text

Abstract: PURPOSE OF THE STUDY: We wanted to determine whether the minimally invasive posterior approach for total hip arthroplasty leads to defective implant positioning or specific complications. MATERIAL AND METHODS: One hundred total hip arthroplasties were performed in 98 patients via the posterior minimally invasive approach using a specific instrumentation between June 2003 and January 2004. All operations were performed by the same surgeon. The series included 59 men. Mean patient age was 61 years (range 25-83) and the mean body mass index as 26.1 kg/cm2 (14.1-40.7). RESULTS: Mean length of the incision was 65 mm (range 45-80 mm). Mean operative blood loss was 393 ml. The VAS decreased from 2.6 on day 1 to 1.0 on day 5. The Harris score rose from 54.5 preoperatively to 85.6 six weeks postop. Mean cup abduction was 43.6 degrees and mean anteversion 16.4 degrees . The center of the hip was restituted within 5 mm in 91% of hips. Stem alignment was 0.8 degrees varus. The femoral offset and the overall hip offset were restituted within 10 mm in 88% of hips. There were no leg length discrepancies greater than 15 mm. Two patients required in addition cup fixation intraoperatively due to acetabular fracture and cup instability. There was one vertical fissuration at the lower end of the stem on one postoperative x-ray. There were no infections nor vascular or neurological lesions. Early dislocation occurred in one 78-year-old patient. There were no revisions for complications. DISCUSSION: Total hip prosthesis implanted via the minimally invasive posterior approach is a difficult operation. Despite the use of specific instruments adapted to this limited approach, the method appear to be safe and to provide reliable results. If the incision has to be widened in a given patient, use of a familiar approach would be advisable. Experience and use of specific instruments enables proposing this technique for the majority of first intention total hip arthroplasties.

Yercan HS, Sugun TS, Bussiere C, Ait Si Selmi T, Davies A, Neyret P. · Department of Orthopaedics and Traumatology, Centre Livet-Hopital Croix Rousse, Rue de Margnolles, 69300 Caluire, France. · Knee. · Pubmed #16490357 No free full text.

Abstract: We investigated the prevalence of stiffness after total knee arthroplasty, and the results of the treatment options in our practice. Between 1987 and 2003, we performed 1188 posterior-stabilized total knee arthroplasties. The prevalence of stiffness was 5.3%, at a mean follow-up 31 months postoperatively. The average age was 71 years (range, 54-88). The patients with painful stiffness were treated by two modalities: manipulation and secondary surgery. In the manipulation group (n:46), the mean range of motion improved from 67 degrees before manipulation to 117 degrees afterward. This improvement was maintained at final follow-up as 114 degrees. There was no significant difference between the motion, immediately after manipulation and at final follow-up. However, motion at final follow-up was better for those manipulated early to those done later (p=0.021). In the secondary surgery group (n:10), the mean gain in motion was 49 degrees at final follow-up and average pain score was found 43. Patellar problems--component loosening and clunk syndromes--were found in 4 patients (40%). Early manipulation gives better gain of motion than done later and our patients had not lost flexion during follow-up. The patella should always be evaluated in every stiff arthroplasty. In our opinion, patellar problems are a good prognostic factor for the success of revision surgery and open arthrolysis does not correct a limited flexion arc, but it does relieve pain. Arthroscopic release is not reliable for severely stiff knees and we prefer to perform it in less painful and moderately stiff knees within 3 to 6 months after operation.

Châtain F, Richard A, Deschamps G, Chambat P, Neyret P. · Clinique des Cèdres, Grenoble. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #14968003 No free full text.

Abstract: PURPOSE OF THE STUDY: We analyzed technical difficulties encountered when performing revision total knee arthroplasty in patients with unicompartmental femorotibial prostheses. MATERIAL AND METHODS: This multicentric retrospective study included 54 revisions of unicompartmental femorotibial prosthesis with implantation of a total knee prosthesis. The series included 45 medial and nine lateral compartment prostheses. A gliding total knee prosthesis was implanted in 53 cases (98%) (39 standard, 14 revision). Mean time to failure of the unicompartmental prosthesis was four years. IKS scores were established at review. The radiological work-up included AP and lateral views in single leg stance and goniometry for 22 medial compartment revisions. Twenty-seven patients were seen for physical examination and x-rays and eight were lost to follow-up; data were recorded from medical files for 19 patients. RESULTS: The revision procedure was considered easy in 82% of the cases. Mean follow-up after revision was four years (range 2 - 12 years). Subjective outcome was very satisfactory for 56% of the patients, satisfactory for 36% and unsatisfactory for 8%. The mean function score was 62 points, the mean knee score 85 points, and the mean flexion was 113 degrees. No laxity was found for 90% of the knees. The femorotibial angle was 180 +/- 2 degrees in 46% of the patients. The mechanical femoral angle was 90 degrees in 54% of the patients with 2-4 degrees varus in 42%. The mechanical tibial angle was 90 degrees in 46% of the patients with 2-8 degrees valgus in 37%. Complications included pulmonary embolism (n=2), mobilization under general anesthesia (n=3), arthrolysis (n=1), lateral vertical patellectomy (n=1), and secondary infection (n=1). There were five failures requiring changing the total knee prosthesis. DISCUSSION: Loss of bone stock raises specific problems during revision of unicompartmental knee prostheses. Loss of tibial bone is more frequent but it is more difficult to correct for loss of femoral bone. A gliding knee prosthesis is generally preferred for first intention revision. We recommend a long stem when the bone defect is important or involves loss of cortical bone. We have had good mid-term results with revision total knee prostheses after unicompartmental prostheses. Longer follow-up is needed. Poor results were obtained when revision was performed for persistent pain without a clearly defined cause. The presence or not of significant bone loss did not appear to affect outcome. The observation of medial laxity in case of failed lateral unicompartmental prostheses suggests a more constrained total knee prosthesis might be indicated. Compared with earlier series, our results with total knee prostheses after unicompartmental prostheses appear to be better than after tibial valgus osteotomy and also better than after total knee arthroplasty. Conversely, they would be less satisfactory than for primary total knee arthroplasty. The surgical procedure for revision total knee arthroplasty after unicompartmental prosthesis requires precision and skill but is not technically difficult.

Châtain F, Marin F, Lavaste F, Skalli W, Neyret P. · Service de Chirurgie Orthopédique et Traumatologie, Hôpital de la Croix-Rousse, Centre Livet, Lyon. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #12503022 No free full text.

Abstract: PURPOSE OF THE STUDY: The level of the joint space can be modified after implantation of a total knee prosthesis. Likewise, ligament balance is a cardinal point of the surgical technique. The purpose of this in vitro work was to study the influence of the position of the distal tibiofemoral joint space after implantation of a total knee prosthesis on the three-dimensional kinetics of the knee joint and on the behavior of the lateral ligaments. MATERIAL AND METHOD: Total knee arthroplasty (TKA) with a posterior stabilized prosthesis was performed on seven fresh-frozen cadaver specimens. A specially-designed experimental device was used to achieve continuous knee motion simulating hip flexion from a vertical position. The Vicon optoelectronic system was used to record the femorotibial and femoropatellar kinematics in three dimensions. Two electronic goniometers were positioned on the insertions of the lateral ligaments to measure ligament displacements during knee movements. Five configurations were recorded on each knee: healthy knee, same knee after TKA, and 2-mm and 4-mm upward displacement of the prosthetic distal tibiofemoral joint space. Ligament balance at extension was preserved in all configurations. The kinematic curves obtained were compared with the coefficient of multiple correlation. RESULTS: Changing the position of the joint space had a significant effect on the kinematics of the patella (rotation and abduction-rotation) but did not have a significant effect on the femorotibial kinematics. Variations in the length of the lateral ligaments were of small amplitude. Lowering the joint space led to laxity at flexion. Raising the joint space tightened the ligaments at flexion. DISCUSSION: These results confirm our clinical impression when the level of the distal femur cut is set to achieve tension on the ligaments at knee extension. If the joint space is lowered, i.e. with a more sparing distal femur cut, the prosthesis takes up less space during flexion, leading to laxity at flexion. If the joint space is raised, i.e. with an excessive distal femur cut, the prosthesis takes up more space during flexion, tightening the lateral ligaments. CONCLUSION: The position of the joint space must be rigorously reproduced during TKA not only to maintain correct femorotibial kinematics, but most importantly to preserve patellar kinematics and proper behavior of the lateral ligaments. Ideally, the height of the joint space should be restored first, followed by control of the ligament balance. An over- or undercut of the femur can lead to defective femoropatellar kinematics and ligament tension at flexion despite good ligament balance at extension. In addition, ligament balance should not be achieved by displacing the tibial cut or by modifying the thickness of the tibial component, which would have an effect not only at extension but also at flexion.

Tayot O, Aït Si Selmi T, Neyret P. · Centre Livet, 8, rue de Margnolles, F-69300 Lyon-Caluire, France. · Knee. · Pubmed #11706727 No free full text.

Abstract: Of 376 cemented posterior stabilized HLS1 TKRs inserted in 329 patients (mean age 70) between 1984 and 1988, information was available on 306 (81.4%) at the third follow-up in 1998: 118 patients deceased; 163 followed up clinically (Knee Society score) and radiographically; 25 revised (15 infections; 10 mechanical failures). At a mean follow-up of 11.5 years, the mean pain score was 43/50, and the mean ROM score 21/25 (both unchanged since 1989). The function score had declined linearly, from 70/100 in 1989 to 60/100 in 1998. Forty percent had tibial radiolucencies correlating with the extent of preoperative bone wear. Polyethylene wear (seen in 35% of knees) was always < 3 mm. The implant survival rate (infections included) was 93.7% (+/- 1.4%) after 10 years. All the mechanical failures were in advanced-OA patients with ACL-deficient knees and major bony deficiencies.

Bonnin M, Deschamps G, Neyret P, Chambat P. · Clinique Sainte-Anne-Lumière, 85, cours Albert-Thomas, 69003 Lyon. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #11104991 No free full text.

Abstract: PURPOSE OF THE STUDY: We reviewed 69 consecutive cases of total knee arthroplasty revisions to analyze the causes of failure. MATERIAL AND METHODS: Sixty-nine total knee arthroplasty revisions were required between 1990 and 1997 for non-septic failure. Five categories of failures were identified: 30 loosenings including 11 with an initial malposition (varus position of the tibial component in 8 cases), 14 laxities (medial in 5, lateral in 5 and anteroposterior in 4), 11 stiff knees with no other clinical or radiological anomaly, 6 patellar failures (2 dislocations, 2 cases of excessive wear, 2 painful knees with a Freeman prosthesis), and 8 cases of painful knees with no other detectable anomaly. RESULTS: A three-phase reconstruction procedure was used after removing the failing TKA: 1) reconstruction of the tibia with replacement of lost bone, 2) reconstruction of the femur with balanced flexion determining the size of the implant, 3) balanced extension determining the distal/proximal position of the femoral component. A "simple" sliding prosthesis was used in 16 cases, a modular reconstruction prosthesis in 40 cases and a hinge prosthesis in 13 cases. Mean follow-up for functional and radiographic assessment after revision surgery was 37 months (59 cases) with a minimum follow-up of 1 year. The best outcome was observed in the "loosening", "laxity", and "stiffness" patients. Outcome was less favorable for the group "isolated pain" with IKS functional scores of 35.5 +/- 16 and 52.5 +/- 21. DISCUSSION: In 36 p. 100 of cases, TKA failure was related to a technical mistake (component malposition, poor ligament alignment). In 33 p. 100, failure was patient related (multiple procedures, congenital hip dysplasia, rheumatoid arthritis.). Outcome after revision TKA was less favorable than after primary TKA, particularly in case of painful knees with no other detectable anomaly. CONCLUSION: Surgical revision of TKA must follow a rigorous procedure with a detailed preoperative work-up. The decision for revision must not be made unless a precise anomaly has been identified.

Zanone X, Ait Si Selmi T, Neyret P. · Service d'Orthopédie, Centre Livet, Hpital de la Croix-Rousse, Lyon-Caluire. · Rev Chir Orthop Reparatrice Appar Mot. · Pubmed #10612143 No free full text.

Abstract: INTRODUCTION: Restoration of the normal mechanical axis of the knee and balancing of the surrounding soft tissues have been shown to have an important bearing on the final outcome of total knee arthroplasty. In knees with severe congenital varum deformity these goals may be difficult to achieve. MATERIAL AND METHODS: In four patients with osteoarthritis and severe congenital knee varum deformity of more than 15 degrees, we performed a high tibial valgus osteotomy with opening wedge, combined during the same procedure with total knee arthroplasty. RESULTS: As correction of the extra-articular deformity was obtained by the osteotomy, in none of the cases it was necessary to perform extensive soft tissue release or advancement to restore alignment. Postoperative X-rays demonstrated restoration of the normal mechanical axis in three cases, but in one case the angular correction of the osteotomy was insufficient and we observed a 9 degrees residual varus deformity. DISCUSSION: The osteoarthritic knee must be mechanically realigned for any total knee arthroplasty to be successful in the long term. Most commonly angular deformities are manifestations of the arthritis process, but sometimes, like in congenital varus deformity of the tibia, part of the deformation can be extra-articular in origin. In these cases, restoring alignment and stability may be difficult to achieve. The association of high tibial valgus osteotomy with total knee arthroplasty permits the correction of the extra-articular deformity, by the osteotomy, without performing extensive soft tissue release, as would be needed in total knee arthroplasty alone. CONCLUSION: Total knee arthroplasty associated with high tibial valgus osteotomy seems to be a technically satisfying alternative in patients with osteoarthritis and severe congenital varus deformity of the tibia.