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Clinical Conference Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis. 1999
Mroczkowski PJ, Weinblatt ME, Kremer JM. · Division of Rheumatology, Albany Medical College, New York 12208-3479, USA. · Clin Exp Rheumatol. · Pubmed #10589360 No free full text.
Abstract: An open-label, one-year study was conducted to evaluate the safety and clinical response to leflunomide and methotrexate combination therapy for rheumatoid arthritis. Study results revealed tolerable safety, no significant pharmacokinetic interactions between methotrexate and leflunomide, and suggested improved clinical response with combination therapy.
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