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Review Primary Gougerot-Sjögren syndrome: a dermatological approach. 2006
Roguedas AM, Youinou P, Lemasson G, Pennec YL, Misery L. · Laboratory of Immunology, Brest University Medical School, 2 avenue Foch, 29609 Brest Cedex, France. · J Eur Acad Dermatol Venereol. · Pubmed #16503880 No free full text.
Abstract: Gougerot-Sjögren syndrome (GSS) is a chronic heterogeneous non-organ-specific autoimmune disease, encompassing a wide spectrum of clinical manifestations. It is characterized by a lymphocytic infiltration of the exocrine glands, also called epitheliitis, resulting in xerostomia and keratoconjunctivitis sicca. The skin can also be involved; for example, xerosis is a consequence of epitheliitis. Dermatological consequences of polyclonal reactivity are vasculitis and manifestations of B-cell proliferation vary from plasma cell infiltrates to B-cell lymphoma.
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