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Review Cutaneous manifestations of primary Sjögren's syndrome are underestimated. 2004
Roguedas AM, Misery L, Sassolas B, Le Masson G, Pennec YL, Youinou P. · Laboratory of Immunology, Brest University Medical School, Brest, France. · Clin Exp Rheumatol. · Pubmed #15485020 No free full text.
Abstract: The association of kerato-conjunctivitis sicca and xerostomia has been termed Sjogren's syndrome (SS). Although this disease is referred to as a non-organ-specific autoimmune condition, the vast majority of the deleterious effects of primary SS are restricted to the exocrine glands. Among them, the lacrymal and salivary glands are at the foreground, owing to the severity of the objective consequences and the importance of the subjective manifestations. As a result, cutaneous manifestations are minimized, albeit relatively common. We have carefully analyzed the literature to draw up an inventory of the possible skin complications of this syndrome. In addition to xerosis and epidermal IgG deposits, they include vasculitis and cutaneous B cell lymphoma. Alopecia, vitiligo and papular lesions have also been reported to be associated with primary SS.
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