Rheumatoid Arthritis: Le Corre R

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A digest of articles written 1999 and later, on the topic "Arthritis, Rheumatoid," originating from Planet Earth —» Le Corre R.  Display:  All Citations ·  All Abstracts
1 Review Abnormal distribution of CD45 isoforms expressed by CD4+ and CD8+ T cells in rheumatoid arthritis. 2000

Mamoune A, Durand V, Le Goff P, Pennec YL, Youinou P, Le Corre R. · Laboratory of Immunology, Brest University Medical School, France. · Histol Histopathol. · Pubmed #10809380 No free full text.

Abstract: CD45RO+ T cells are referred to as memory or helper-inducer while CD45RA+ T cells are regarded as naive or suppressor-inducer T cells. The former population predominates in the peripheral blood and even more in the synovial fluid of patients with rheumatoid arthritis, to the expense of the latter population. Within the CD45RB+ compartment, there appears to be more of the fully-differentiated than of the early-differentiated CD4+ T cells. In spite of the fact that these lymphocytes are close to undergoing apoptosis, this programmed cell death is inhibited in the rheumatoid synovium.