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Article Stress, emotion and the heart: tako-tsubo cardiomyopathy. 2006
Iqbal MB, Moon JC, Guttmann OP, Shanahan P, Goadsby PJ, Holdright DR. · Department of Cardiology, The Heart Hospital, London, UK. · Postgrad Med J. · Pubmed #17148696 No free full text.
Abstract: Tako-tsubo cardiomyopathy is a cardiac syndrome precipitated by profound emotional stress and anxiety, particularly in middle-aged women. It presents as a mimic of acute myocardial infarction, but coronary angiography shows normal coronary arteries and a characteristic left ventriculogram resembling an "octopus pot". The condition seems to have a favourable prognosis. Initially described in Japan, and with many names in the literature, it is being increasingly recognised in the West owing to early coronary angiography and primary coronary intervention, accounting for up to 1 in 30 primary cases of angioplasty in some institutions. A typical case is described, and the clinical features, pathophysiology and management reviewed.
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Retraction Psychiatric side effects during methysergide treatment. free! 2005
Cittadini E, Goadsby PJ. · Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK. · J Neurol Neurosurg Psychiatry. · Pubmed #15965225 links to free full text
Abstract: A patient is reported with psychological change characterised by impaired concentration and thought projection, followed by both severe anxiety and depression, starting after three weeks on high dose methysergide. The acute problem settled slowly after methysergide withdrawal and is likely to represent an unusual and serious side effect of that drug.
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